Abstract: In the context of urban renewal that emphasizes both “cultural memory inheritance” and “spatial scene translation”， the adaptive reuse of old industrial plants into art galleries has become a significant practice. However， the coupling mechanisms between old and new spaces and the pathways for cultural information translation in this transformation require deeper analysis. From the theoretical perspective of spatial coupling， and through a comparative analysis of spatial conditions before and after adaptive reuse in typical cases， this study deciphers the intrinsic logic of interaction between industrial heritage attributes and the functional requirements of art galleries. This study reveals that the adaptive reuse of spatial functions primarily achieves coupling across two dimensions—the physical architectural spatial system and the perceptual experience system—through specific spatial translation pathways： juxtaposition， contrast， integration， and guidance. Consequently， an adaptive design model structured at three levels is formulated： macro-positioning （serving as urban landmark anchors and community engines）， meso-organization （featuring linear series， hall nesting， and grid permeability based on the translation and reconfiguration of structural logic）， and micro-interface （employing trace visualization， material dialogue， and transparency intervention）.