Viscous damping wall is an innovative high efficient energy dissipation device for reducing the dynamic responses of building structures. It has a preferable effect of suppressing the vibration amplitude of the building structures under both earthquake and wind. The element design of the structure can be optimized since the internal force of structure member has been reduced by additional damping ratio provided by the viscous damping wall. A new method of integrated optimal design of tall building structures with viscous damping walls was put forward. Both the anti-seismic performance objective and size control condition of members for the tall building structure were explored, the appropriate arrangement of the viscous damping wall could make the structure comply with the design requirement. The optimal position of the viscous damping wall based on integrated optimal design was applied on a 300 m super tall building of central core tube and braced frame,the result revealed: the integrated optimal design of tall building structures with viscous damping walls have economical benefit for the structure.