This paper introduced the general situation of thethird frontconstruction in Guizhou Province first,and then analyzed the heritages status of thethird frontindustrial buildings in Guizhou Province. A thorough thinking about the value evaluation and the dilemma of protection ofthird frontindustrial building heritages; and finally,it was put forward the method of heritages protection and reuse of thethird frontindustrial buildings in Guizhou Province.