In order to study the optimum design method for pile-raft foundation of ecological composite wall structurebased on interaction between structure, subsoil and foundation, a compute model of ecological composite wallstructure and shear wall structure based on interaction was founded.The inner force and deformation of structure andfoundation were calculated.In light of the result, the influence of interaction stress and strain of pile-raft foundationand soil was analyzed.And the calculation results of two types of structures were contrasted to research the effect ofchange of thickness, strength of concrete of raft, length, diameter of pile on stress, strain of structure andfoundation, reacted force of pile top, the share proportion of load of pile and raft.Which can provide reference foroptimum design method of pile-raft foundation of ecological composite wall structure based on interaction of subsoil, foundation and structure.