Abstract: Taking the metal roof of Hangzhou-Shaoxing-Taizhou Railway Station as the research object, through the wind resistance test, its failure mode and wind resistance were determined, and the effects of different parameters on the wind resistance of standing seam metal roof were discussed, the results showed that the main failure mode of the standing seam metal roof under wind suction was trip-out failure between the roof panel at seams and bearings. changing the bearing height, purlin spacing and arranging the anti-wind clip could improve the wind resistance of the metal roof with standing seams, and the effect of arranging the anti-wind clip was the most significant. The high-strength wind resistance clamp could change the failure mode of metal roofing system and greatly improve the wind bearing capacity of roof panel compared with the conventional wind clamp. Dynamic cyclic loading had an obvious influence on the ultimate bearing capacity of metal roof with standing seams. It is very necessary to carry out dynamic cyclic wind resistance test in practical engineering.