Abstract: In recent years, with the continuous progress of national urbanization and the deepening of the concept of heritage protection, industrial heritage, as a symbol of the industrialization era and an important part of urban history and culture, has become one of the main contents of urban renewal. Taking the industrial heritage along the Pearl River in Guangzhou, Guangdong Province as the research object, the paper analyzed its distribution characteristics and internal value, introduced the heritage corridor mode of industrial heritage protection and utilization in view of its current characteristics and existing problems, and puts forward that in the protection and utilization of industrial heritage along the river, a diversified development, protection and utilization strategy of the internal space construction of the corridor was proposed by constructing the industrial heritage utilization system, dividing the corridor level, and refining the internal structure. The protection and management was strengthened, as well as the benign interaction with the city, in order to provide a reference for the activation and utilization of the same type of industrial heritage.