Abstract: The concealed fastener metal roofing panel has been widely used because of its simple structure, convenient installation and ensuring waterproof effect. However, its connection mode mainly depends on the snap connection at the wave crest. When the wind uplift is large, the arching deformation of the wave trough is easy to lead to the excessive deformation of the wave crest, which is separated from the support. In coastal areas, this type of roofing panel is lifted from time to time. Because the stress between the plate and the support is complex and difficult to simulate, Technical Code for Application of Profiled Metal Sheets(GB 50896-2013) clearly requires that the profiled metal roofing system should be tested to verify the overall wind-uplift resistance capacity. Through the analysis and research on the use, structural principle and damage of the concealed fastener roofing panel, targeted reinforcement measures were put forward. The damage wind pressures of CC750 concealed fastener roofing panel before and after reinforcement were obtained according to the wind-uplift resistance test, which the best reinforcement combination scheme could be selected. Finally, according to the test results and the actual situation, practical reinforcement measures and suggestions were put forward.