Abstract: The design of renewal and reuse for old industrial buildings has always been a focus of high attention by all walks of life in contemporary society. With the rapid development of the national economy, land resources in cities have become increasingly scarce, and a large number of old industrial buildings in the old industrial base cities are facing many problems such as elimination, reconstruction or upgrading. At the same time, with the continuous improvement of the people's material living standards, the citizens' pursuit of culture and art has become more and more intense. The renewal design for transforming abandoned industrial plants into public art spaces is one of the important measures with the background of urban sustainable development and the cultural industry reviving. Starting from the development status of the old industrial base in Liaoning, taking Shenyang Cultural and Creative Cluster Quarter of Hongmei 1939 project as the research object, the rationality of the reform for the block was expounded based on the spatial syntax theory. The paper sorted out and expounded the regeneration strategy of converting abandoned industrial plants into public art spaces from the aspects of historical value, practical functions, interior decoration, design style, etc. The meaning and value of the “industrial image transformation” that transforming abandoned industrial plants into public art spaces were summed up.