Abstract: To study the mechanical behavior of the modular box-type integrated house structure under the horizontal cyclic loading, the quasi-static test of the full-box structure under the combined vertical and horizontal loading was carried. In the test, the vertical load was equivalently replaced by the weight, and the horizontal load was equivalent to the joint load. The overall mechanical behavior of the box was evaluated by the combined effect of the above loads. The test results indicated that the vertical deformation of specimens under the vertical loading was small, and the specimen was not damaged. Under the horizontal cyclic loading, the upper and lower connectors played a good connection. During the entire loading process, most of the strain data of the measuring points were within the elastic range. In the loading and unloading process of the specimen, the specimen was in intact except partial damage and falling off of the partial wall panel and the auxiliary structure, which meet its safety requirements.