Abstract: In order to study seismic responses of industrial workshops with SRC hybrid structure, an actual industrial workshop was simulated and analyzed by the finite element software SAP2000. Through modal analysis, response spectrum analysis, elastic time-history analysis and elastic-plastic time-history analysis, the results showed that the period ratio of the structure was less than 0.9. Under frequent and rare earthquakes, the maximum drift angle of stories by the modal decomposition method for response spectrum and elastic time-history analysis was 1/717, and the peak drift angle of the top floor analyzed by elastoplastic time-history was 1/81, both of which met the requirements of the specification GB 50011-2010 on the drift angles. The displacement responses and acceleration responses of the structure increased with the increase of earthquake intensities, and the instantaneous energy dissipation mainly occured in the peak acceleration periods, and the energy dissipation under rare earthquakes was much higher than that under frequent earthquakes.