Abstract: The design of long-span curved surface structure is the difficulty of spatial structure. Especially in the curtain wall design, the connection with the main structure needs to be considered, and there are few cases. The paper described the steel structure design process for long-span curved surface curtain walls of Shanghai International Aviation Service Center. The upper part of the curtain wall connected the main structure of the tower, and the lower part diverged horizontally to the podium, which connected the two with a natural curved surface, formed a skirt effect, and realized the unity of architectural aesthetics and structural design concepts. In the long-span curved surface part, the grid was formed by parameterization, and the longitudinal open web quilting frame and the secondary beam were determined. In the middle part, the cross cable system was designed to form the overall stiffness in the plane. The steel structure of curtain wall was connected with the main body through tree column and tower extension rod, forming a complete structural system. Finally, finite element analysis software was used to perform elastic static analysis, static geometric non-linear analysis, elastic time-history analysis, and checking verification of key members, all indicators could meet the construction requirements.