Abstract: Based on the OpenSEES software，the expressions of the constraints between the parameters of beam and column under the desired failure mode of SＲC frame structure ( beam hinge failure mechanism) were set up． The optimal objective of the parametric model was realized by a program ANSYS and the genetic algorithm was chosen to optimize the multi-objective optimization model of the minimum cost and ideal failure mode． The specific process of optimization would be given through an engineering example，meanwhile the comparison and analysis of optimization results with original scheme would be made on economic benefits． At last，the effect of weighting coefficient and genetic algorithm parameter settings on the optimization result of optimal model was discussed．