Abstract: The latest progresses of biomineralization showed that some kinds of microbes could induce calcium carbonate quickly by using the ambient urea and calcium ion source． These calcium carbonate crystals could be used as binders to bind loose sands to artifical stones whose strength and permeability could be controlled． In the author's research，22 strains producing urease were isolated from soils，including four strains producing high activity urease， which had ability to induce calcium carbonate precipitation． They respectively belonged to Bacillus and Sporosarcina genus by identification of 16S rDNA． Sand column grouting was tested by each stain respectively，the results showed that uniaxial compressive strength of these sand columns were between 0. 2 to 2. 4 MPa which would have application potential in treatment of foundations．