Abstract: The progressive collapse resistance of the large-span pre-stressed spatial structures raises widely concerns. A new-type pre-stressed cable-strut structure whose typology is advantageous to resisting progressive collapse, named Annular Crossed Cable-truss Structure (ACCTS), is proposed. In aim to prove the progressive collapse resistance of the new-type structure, simulations based on Instantaneous Component-Removing Method of ANSYS/LS-DYNA are put forwards. Instantaneous removals of different kinds of cables or rods are considered respectively. It turns out that the ACCTS doesnt turn geometrically unstable in all removal conditions. Increasing the strength reserve as appropriate makes senses and becomes effective way to resist progressive collapse.