Abstract: With the adjustment of the industrial structure of the city，much attention is being paid gradually to the renovation and reuse of old industrial buildings． However，during the renovation of old industrial buildings and in the process of their reuse，there are some significant or potential risk factors in structure，management，environment， policies and regulations，ideology，etc． Based on field research on 24 old industrial buildings，23 risk factors were idertitied which affect the renovation and reuse of old industrial buildings． Ｒelated statistical data were obtained by questionnaires and the key influential factors were drawn out with principal component analysis method． Therefore， six main factors were pointed out that influence the renovation and reuse of old industrial buildings． Accordingly， some related countermeasures were presented，which may be references for the promotion of the renovation and reuse of old industrial buildings．