Abstract: In Chinese modern times，there were a large number of industrial commercial buildings built in Wuxi City because of the rapid development of industry and commerce in the city. Combined with the construction instance，it was described the industrial and commercial development history of Wuxi in modern times. At the meanwhile，based on the concept of constructing structures and buildings led by commodity economy，it was tried to discuss and analyse the causes and characteristics of the different styles of industrial commercial buildings of Wuxi in morden times from three levels. It was revealed that the vital relations among the construction of buildings，the consciousness of commodity economy and generalization in industrial and commercial development of Wuxi in modern times.