Abstract: The temperature deformation analysis of a long industrial plant structure was carried out.The temperature loads included the weather changes, such as seasonal temperature changes, sudden temperature changes and sunshine temperature changes, and the effect of concrete shrinkage.The normal limit state load standard combination was adopted.The finite element software ETABS was used for simulation to study the structural temperature deformation.Furthermore, structure II was set up for research of the influence of the situation of the expansion joints on the temperature deformation of the structure.Finally, a simplified frame model was built to expose the distribution law of the structure's internal force and deformation in multi-stories or high-rise structures with large longitudinal length.Some reasonable suggestions on the position of expansion joints were presented, which could save the construction cost, improve the using effectiveness, and could be referenced for engineering construction.