Abstract: The multi-ribbed composite wall is a new building structure which possesses the characteristics of the load-bearing,enclosure,energy saving and anti-seism.It is monolithically cast of the invisible frame、prefabricated multi-ribbed composite wall and the floor,which has multi-line to act against earthquake and can release earthquake energy by stages.In view of the fact that the act against earthquake response is closely related to the wall lateral stiffness,it is established the nonlinear finite element model of the multi-ribbed composite wall with ANSYS based on the experiment study.Under interaction of the horizontal load and the vertical load,different FEA models are built with different materials,almost a linear correlation between filled block elastic modulus and the wall's lateral stiffness,comparing the analysis result with the experiment one shows,that the model has certain practical value,which can provide reference calculations for the structure design.