Abstract: The purpose of this paper was to observe and analyse the related issues of the application of steel plate reinforced concrete structure in nuclear power engineering，focusing on how to apply the new type of structure to the type of complex projects of high safety importance such as nuclear power plant． The advantages of steel plate reinforced concrete structure were pointed out． This type of structure could improve both of the safety and the reliability of nuclear power engineering，and it was favorable for promoting the standardization and the modularity of the design and the construction of future nuclear power plant and also for the implementation of shorter construction cycle and lower project risk． It was also pointed out the problems，to which attention should be gave attention to and should be solved in the application of steel plate reinforced concrete structure in nuclear power engineering and a series of scientific and technical problems should be solved in the design，construction，testing，quality control and quality assurance．