Abstract: The vibration behavior of beam-plates system caused by the vibration of fluidized bed dryer was tested． The disturbing force and frequency of vibrating equipment，working performance of the existing isolation bearing and response of floor vibration was obtained． According to the spot test results， finite element analysis of simple harmonic vibration was carried out by ANSYS software． The test results show that floor vibration response is larger in frame regions having vibration equipment; vibration response of monitoring points on frame beam is much less than that of monitoring points on secondary beam，vibration response of measuring points decay soon along the floor longitudinal points． The linear superposition comprehensive vibration effect of multiple vibration equipment can be regarded as a single vibration equipment vibration effect，the main cause of factory floor of big vibration is forced resonance． Based on a simply continuous orthotropic plate model and the eigenfrequency sensitivity analysis technique，the optimal modifying position and revisions of the structural stiffness were acquired． Lastly，the vibration reduction treatment scheme was proposed．