Abstract: Based on the experimental study on a lattice steel reinforced concrete frame with special-shaped columns under low cyclic reversed loading，the mechanical process and failure patterns were observed． The load-displacement hysteretic loops and skeleton curves and the load and displacement at different stages were obtained． The seismic behaviors such as inter-story drift ratio，ductility，energy dissipation and stiffness degradation were analyzed． Test results show that the failure mechanism of the structure is the beam-hinged mechanism，and it is a typical strongcolumn and weak-beam structure． The hysteretic loops are plump，and the stiffness degradation is unconspicuous． The ultimate elastic-plastic story drift rotation is larger than the limit value specified by the code，demonstrating the high capacity of collapse resistance． The ductility and energy dissipation of the structure are better than that of the reinforced concrete frame with special-shaped columns．